Journal of The Arab Society for Medical Research

ORIGINAL ARTICLE
Year
: 2016  |  Volume : 11  |  Issue : 1  |  Page : 14--21

Occupational exposure to hepatitis infection among Egyptian healthcare workers and hepatitis B vaccination


Dalal M El-Melligy1, Amal Saad-Hussein2, Sahar A Khalil3 
1 Department of Microbiology, Ahmed Maher Teaching Hospital, Cairo, Egypt
2 Department of Environmental and Occupational Medicine, National Research Centre, Cairo, Egypt
3 Infection Control Committee, Ahmed Maher Teaching Hospital, Cairo, Egypt

Correspondence Address:
Amal Saad-Hussein
Department of Environmental and Occupational Medicine, National Research Centre, Cairo
Egypt

Background/aim Healthcare workers (HCWs) are at a high risk for blood-borne pathogens due to their contact with patients and contaminated instruments. The present study aimed to determine the risk of exposure to hepatitis B virus (HBV) and hepatitis C virus (HCV) infections among Egyptian HCWs in relation to the level of infection control education, the number of hepatitis B vaccine doses received, and the resulting immunity. Participants and methods This cross-sectional study was conducted on 228 HCWs. Hepatitis B surface antigen, hepatitis B core antibody, hepatitis B surface antibody titer, and hepatitis C virus antibody (HCV-Ab) were tested by using the enzyme-linked immunosorbent assay technique. Real-time PCR for both HBV-DNA and HCV-RNA in serum was done with positive hepatitis B surface antigen and HCV-Ab, respectively. Results During the study period, 78% of the HCWs received full HBV vaccination; 73.6% of them were vaccinated in the last 5 years. Lack of protective hepatitis B surface antibody (HBs-Ab) titer was found in 27.2% of the participants. HCV-Ab was positive in 6.14% HCWs, being significantly higher in individuals 40 years of age or older when compared with those under 40. Half of those with positive HCV-Ab had HCV-RNA below the detection limit. Conclusion Implementation of infection control guidelines played a role in reducing the prevalence of HCV infection among HCWs and in vaccinating HCWs in the last 5 years. Adopting safety-engineered devices is required to help in the reduction of needle stick and sharp medical devices injuries and risk for blood-borne infections.


How to cite this article:
El-Melligy DM, Saad-Hussein A, Khalil SA. Occupational exposure to hepatitis infection among Egyptian healthcare workers and hepatitis B vaccination.J Arab Soc Med Res 2016;11:14-21


How to cite this URL:
El-Melligy DM, Saad-Hussein A, Khalil SA. Occupational exposure to hepatitis infection among Egyptian healthcare workers and hepatitis B vaccination. J Arab Soc Med Res [serial online] 2016 [cited 2020 Dec 1 ];11:14-21
Available from: http://www.new.asmr.eg.net/article.asp?issn=1687-4293;year=2016;volume=11;issue=1;spage=14;epage=21;aulast=El-Melligy;type=0