Figure 3 A photomicrograph of liver tissue sections. (a) Normal structure of this tissue. (b) Rats treated with toluene show dilatation and congestion of blood sinusoids. Some cells show strongly eosinophilic-stained cytoplasm with small nuclei. (c) Rats treated with toluene and 150 mg citicoline, where dilatation and congestion of blood sinusoids are still noticed, whereas most of hepatocytes appear normal. (d) Rats treated with toluene and 300 mg citicoline show normal liver tissue structure (hematoxylin and eosin, ×200, ×400).